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Smoking and Nicotine
To quit smoking has become one of the primary concerns of modern society. People have come to realize the ill effects of cigarette and tobacco which include respiratory disorders and a rare circulatory disease called Buerger’s disease.

Nicotine is one of the nearly 200 substances in tobacco. It affects the human physiology by stimulating the adrenal glands to increase the flow of adrenaline. The blood vessels become constricted and the skin temperature drops, producing effects not unlike exposure to cold temperatures.

When comparatively large amounts of nicotine are absorbed by the body, the pulse becomes rapid and the smoker has symptoms of dizziness, faintness, and sometimes nausea and diarrhea. The release of adrenaline, triggered by nicotine, will produce relief from fatigue by increasing the flow of sugar in the blood. However, the effect is transient, and the feeling of fatigue will return again after the increased blood sugar has been expended.

Other Properties of Tobacco

The nicotine in tobacco can be absorbed simply by contact with the mucous membranes of the mouth; the tobacco does not have to be smoked to get the nicotine effects. Burning tobacco produces a myriad of substances found in the smoke of many plant materials when they are dried and burned. More than 50 different compounds are known to occur in concentrations of one microgram or more in each puff of tobacco smoke.

Again, laboratory tests have demonstrated that the substances in burning tobacco do not have to be inhaled; most of the chemical compounds can be absorbed through the mucous membranes while a puff of smoke is held in the mouth for few seconds. At least ten of the substances in tobacco smoke have been shown to produce cancer in animals. Other chemicals in tobacco tars are known as cocarcinogens; although they do not produce cancer themselves, they react with other substances to produce cancers.

Smoking and Disease

The relationship among tobacco smoking and cancer; heart disease, and emphysema-bronchitis is well established, even if some of the cause and effect links are missing. Large-scale studies of the death rates of smokers and nonsmokers have been carried on for more than 20 years. One group, consisting of nearly a quarter-million war veterans, yielded  results indicating that smokers are from 10 to 16 times as likely to die of lung cancer as nonsmokers. (The higher ratio is for heavy smokers.) Similar results have been obtained studies of smokers and non-smokers with heart disease and lung ailments.

Buerger’s Disease

One of the possible, although rare, effects of smoking is the aggravation of symptoms of a particularly insidious circulatory disorder known as Buerger’s disease. As noted above, one of the effects of nicotine is a drop in skin temperature.

Smoking a single cigarette can cause the temperature of the fingers and toes to drop as much as 15 degrees Fahrenheit; the average is a little more than a 5-degree drop. The temperature change results from constrictions of the blood vessels at the extremities.

Blood clots may develop in the vessels that have been constricted, cutting off the flow of blood to the tissues of the area. When there is numbness or pain in the extremities, the condition should receive swift medical attention to prevent serious consequences.

 
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